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doi: 10.1016/j.bbrc.2011.10.151

10 ml maximum volume for a nicotine containing refill Restrict nicotine containing e-liquids to a strength of no more than 20mg/ml Child resistant and tamper evident However, the fatal dose of nicotine can be as little as 1mg/kg, with a possible refill content of 200mg

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The most recent study of individual CpGs conducted with the Illumina 450K Methylation BeadChip suggests that exposure is associated not only with global changes but also with changes at specific CpG sites (Joubert et al., 2012)

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