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It has been shown that SIRT3 can suppress inflammation by decreasing the expression levels of NF - kB , high mobility group box 1 ( HMGB1 ), c - Jun , c - Fos , cyclooxygenase-2 ( COX2 ), TNF - , IL - 1 and IL - 6 [149]

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It also hopes to help keep tobacco out of schools and delay the age that teenagers start using tobacco.

Mian et al

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