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As opposed to closed pod systems like JUUL, open vaping involves refillable tank-based e-cigarettes that give users control over variables like e-liquid, wattage, and coil type

Of those included, 14 studies (78 foci) reported gray matter decreases among smokers and 5 studies (10 foci) reported increases

Although HTPs have been around since 1988, they've recently gained popularity, changing the landscape of tobacco use globally

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