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Thank you. A note of irritation had entered Kurochkins voice

The smoke contains thousands of compounds and most are considered to be highly toxic

A member of the Pharmacy Class of 1958, Maurice Wolfish was an avid collector of pharmacy memorabilia

Tobacco smoke has many effects on those breathing it, including: Inflammation of the airways, causing them to narrow Increased mucus production Damage to cilia, allowing mucus to clog airways and worsen symptoms Decreased lung function Severe symptoms, which may trigger asthma attacks What about allergies and secondhand smoke

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I highly recommend reading Proctor (2012) for further information, but in general the scientific evidence from the 1930s to the 1950s was accumulating in four areas of research: Population studies people who smoked had higher rates of lung cancer Animal studies tobacco caused tumors in model organisms Cellular pathology cigarette smoke was shown to deaden the hairlike cilia in the lungs upper airway Cancer-causing chemicals in cigarettes cigarette smoke contained polycyclic aromatic hydrocarbons (PAHs), which had been previously shown to cause cancer in people exposed to coal tar Multiple lines of evidence converging like this, linking a health effect with a specific factor, is one of the important ways that epidemiologists assess whether an exposure like smoking a cigarette can cause a detrimental health outcome