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The mechanism of arsenic neuropathy may be similar to the neuropathy of thiamine deficiency [Sexton and Gowdy 1963], whereby arsenic inhibits the conversion of pyruvate to acetyl coenzyme A and thus blocks the Krebs cycle

Activated carbon filters may reduce some tar, but how much depends on: The amount of carbon in the filter The size and design of the filter Airflow and how tightly smoke is pulled through How hot the smoke is How fast a person inhales Carbon filters often include other materials too, like paper or fiber, which can also catch particles

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Axel : [nasally voice] You're not gonna fall for the banana in the tailpipe