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While Phase II trials in heart failure and primary mitochondrial myopathy did not meet primary efficacy endpoints, the TAZPOWER trial in Barth syndrome demonstrated significant improvements in muscle strength and sixminute walk distance, leading to FDA accelerated approval in 2025 [3][10]

Bergmann, N

With earnings per share of $0.38 against a $2.66 annual dividend, the company pays out approximately 700% of earnings as dividends

This aggressive but controlled ramp-up helps the body adjust to the triple receptor activation while minimizing the gastrointestinal distress that comes with too-rapid dose increases

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Contrary to the previous studies which compared BDNF level in the FM patients with the healthy subjects without pain, we chose the non-FM group from patients with NP to elucidate the role of serum BDNF more clearly in the different pain types