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The effects of e-cigarette use on objective cardiopulmonary endpoints in teenagers remain essentially unstudied

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However, despite its protective role, the constant activation of the Nfr2 pathway in response to e-cigarette use, particularly the flavouring agents found in e-cigarettes, can exhaust this protective pathway, leading to eventual cellular death in the epithelium (Ma et al

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How the study was done For the study, Jacobs and his co-authors analyzed smoking information on more than 6,600 people from the United States, Australia and Finland who were followed from childhood into midlife as part of the International Childhood Cardiovascular Cohort Consortium