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While inhaled, cannabis smoke does initiate certain biological activities in the body and brain, but these are not determined to be detrimental

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Low wages, hazardous working environments (including exposure to tobacco dust and repetitive strain injuries), and significant gender pay gaps are widespread

Indeed, enforced expression of mutant p53 in p53-deficient mouse or human cell lines has been reported to lead to new phenotypes [91], supporting the GOF effects of mutant p53