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We would again recommend the Winix 5500-2

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The claims made by Nicotine River, ECBlend, and other vendors that their product provides the same great sense of satisfaction, pleasure and enjoyment as nicotine and Nixotine may be addictive or Nixodine is carefully designed to target the same nicotinic acetylcholine receptors that traditional nicotine stimulates suggest that these products are either marketed with inaccurate information or do contain an additional nicotinic receptor agonist

In fact, it could hardly have been earlier

The variables included socio-demographic profile, smoking status and history, and perceptions of plain cigarette packaging