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For example, in Brazil, Mexico, Argentina, Colombia and Uruguay, the use of electronic cigarettes is absolutely prohibited, in other countries such as Australia and New Zealand there are more restrictive policies as nicotine is considered a poison

In the United States, the implementation of stringent tobacco control policies, coupled with extensive public health programs and the advent of cutting-edge medical technologies, has markedly diminished both the prevalence and incidence of larynx cancer 18

Slow nicotine metabolizers exhibit lower levels of inflammation (ICAM-1 and PGEM) compared to fast metabolizers, which is linked to kidney damage (44)

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