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All mice were bred in the animal facility at Guangzhou Medical University Laboratory Animal Centre, where they were maintained under specific pathogen-free conditions on a 12 light/12 dark cycle at 1824 C and 4060% humidity

Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2014 [accessed 2017 Apr 20]

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