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Some of the following changes may suggest that cocaine use has become a serious issue: Sudden mood swings, irritability, or bursts of confidence followed by exhaustion Frequent sniffing, nosebleeds, or a constantly runny nose Noticeable weight loss or reduced appetite Unexplained financial problems, secrecy, or borrowing money Withdrawal from friends, family, or normal activities Five ways cocaine addiction hides in plain sight Unhealthy relationships with cocaine usually creep in slowly

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"And, truth be told, unlike in my high-school days, Im no longer certain that the future Ive been preserving myself for is all that promising

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They have real, measurable physiological effects and these physiological effects, at least the couple that we found, have been associated with heart disease.

Prolonged duration of type 2 diabetes is associated with increased thrombin generation, prothrombotic fibrin clot phenotype and impaired fibrinolysis