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Stuart said the age of 21 is a political judgment that he feels most people now support as more studies show the danger of smoking and who is providing cigarettes to teenagers and it also matches the age for drinking

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This observation could be due to the limited donor size and the lack of information of non-COPD donors on sex, age and smoking status, which could potentially obscure differences between COPD and control-derived cells with respect to mitochondrial gene expression and methylation