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Keeping this in mind, the following are generally accepted indications for HBOT in the setting of carbon monoxide poisoning Loss of consciousness associated with exposure Altered mental status Focal neurologic changes Evidence of end organ ischemia (pH 7.1, EKG changes, elevated troponin, angina) Pregnancy (with some resources citing a level 20%) Carboxyhemoglobin level 25% Importantly, these are not hard and fast rules and there is no firm guideline mandating when HBOT should or should not be used

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