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In its wisdom, the FDA has deemed pipes tobacco products, a category of things it regulates under the Family Smoking Prevention and Tobacco Control Act (TCA) of 2009

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As the health effects of vaping cannot be accurately assessed, researchers are urging caution before making conclusions

Moreover, the urine levels of metabolites of acrylonitrile, acrolein, propylene oxide, acrylamide and crotonaldehyde, all of which are detrimental for human health, were significantly higher in e-cigarette -only users than in non-smoker controls, reaching up to twice the registered values of those from non-smoker subjects (Table 1) [9]