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Furthermore, studies have shown that, as a regulatory mechanism, there is an increase in expression of GLUT1 through activation of phosphoinositide-3 kinase (PI3K)/Akt pathway via hypoxia-inducible factor-1 (HIF-1) (Yeh et al., 2008)

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we were just lucky enough to have gotten noticed and get attention. Gonzalez admits this sudden virality was jarring: We immediately hit a wall

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Those aged between 25 and 34 years were the most likely to smoke, with 19% in that age group being a smoker

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