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The latter time interval coincides with the introduction of vaping, with many smokers replacing at least some of their regular cigarettes with e-cigarettes

It has also been seen to cause more serious neurological issues, such as tonic-clonic seizures, and pseudo-Cushing syndrome

Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion

Many concentrates are sensitive to light and heat, which can degrade their quality over time

The two types of e-cigarettes are known as open systems and closed systems

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