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doi:10.1016/0091-3057(92)90535-N

Methylation of the FHIT promoter in nicotine-treated cells resulted in modified expression of genes like the anti-apoptotic genes p53 and p16, which promoted growth and proliferative advantages

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In previous research, Benam's group found that vitamin E acetate, a common additive in e-cigarette liquid that contains THC (the psychoactive ingredient in marijuana), generates tiny toxic particles that lodge in the small airways in the lungs and walls of the trachea and bronchus