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When you quit cold turkey, your body will get rid of all the nicotine within 48 hours and begin to experience many health benefits, including: Your heart rate will start to return to normal within 20 minutes Your blood pressure should begin to return to normal after 6 hours The excess carbon monoxide in your blood will be removed after 12 hours Oxygen will be much better circulated throughout your body and energy levels will increase within 72 hours Circulation improves within 2-12 weeks Skin becomes refreshed within 1 month Coughing and sneezing reduces in 3-9 months The risk of heart attack is reduced by 50% within one year The risk of lung cancer is reduced by 50% within 10 years Withdrawal Symptoms Nicotine is an addictive substance, which is why people who stop smoking often experience withdrawal symptoms