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DAVID analysis of downregulated proteins yielded six significant clusters, which included extracellular matrix, cell adhesion/migration, fibronectin, endoplasmic reticulum, actin cytoskeletal signaling, and actin filament binding, implicating the cytoskeleton as a major target (Fig

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Especially with morbid obesity, the pressures on the abdominal wall are so great that they pull the hernia back apart. Dr

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