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Neither active caspase-1 (p20) nor cytokines such as IL-1 and IL-18 were detected in supernatants, which is consistent with prior studies [3]

A modified version of the FTND for assessment of smokeless tobacco users has also been developed.(18) In addition, a reduced version of the FTQ has also been proposed: the Heaviness of Smoking Index (HSI), which consists of two questions (FTQ questions one and four) related to the need for nicotine replacement and to the level of tobacco consumption.(19) Studies evaluating the HSI and comparing it to the FTND have shown that the HSI results are similar to those obtained with the FTND.(8,9,11,20-22) The objective of the present study was to perform a critical review of articles in the indexed literature related to the psychometric properties of the FTND