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Spontaneous reports cannot prove causation or incidence

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Dosage & Clinical Uses Clinicians begin with a low dose of hydromorphone and increase the dose as necessary, which allows them to manage an individuals pain while monitoring both their level of analgesia and adverse side effects (sedation and respiratory depression) throughout the course of treatment

Curr Surg Rep 8 , 27 (2020)

This helps maintain consistent research documentation and reduces calculation errors