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The pathogenesis of COPD. Cigarette smoke activates macrophages (1), Download Scientific Diagram A model of the pathogenesis of COPD. Cigarette smoke and other Download Scientific Diagram Top Facts about COPD and Smoking Smoking causes slow but serious damage to your lungs, often without noticeable signs in the beginning. Each cigarette sends thousands of harmful chemicals into your lungs and air passages. Over time, this Smoking doesn't just affect your lungs it destroys them over time. COPD (Chronic Obstructive Pulmonary Disease) is one of the most common and preventable causes of breathlessness and lung failure. The COPD: Hiding smoking history delays diagnosis Happiest Health

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