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The CDCs overview of why quitting is hard lays out this cycle in plain language: repeated nicotine exposure trains the brain to expect it, and then absence feels uncomfortable

Impact of smoking reduction on lung cancer risk in patients with COPD who smoked fewer than 30 pack-years: a nationwide population-based cohort study

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"Our results are compatible with the idea that cannabis may increase the risk of developing depression or bipolar disorder, but we cannot prove this for certain, since we are working with observational data," explained lead researcher Dr