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In a comparative study, repeated exposure of human gingival fibroblasts to CS condensate or to nicotine-rich or nicotine-free e-vapour condensates led to alterations in morphology, suppression of proliferation and induction of apoptosis, with changes in all three parameters greater in cells exposed to CS condensate [29]

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This process produces dioxygen and hydrogen ions, which are necessary for ATP phosphorylation (Paul et al., 2022)