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explored that the microbial profile of smokers with moderate to severe chronic periodontitis and demonstrated significant differences in the prevalence and abundance of disease-associated and health-compatible organisms, with greater abundance of Parvimonas , Fusobacterium , Campylobacter , Bacteroides , and Treponema and lower levels of Veillonella , Neisseria , and Streptococcus [58]

[DOI] [PubMed] [Google Scholar] 72.MacHet L, Httenberger B, Georgesco G, et al

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A novel mitophagy activator, UMI-77, alleviated apoptosis of RTEC and interstitial inflammation by activating mitophagy, inhibiting TGF-1/Smad-mediated MFB activation and hindering renal fibrosis ( 4.2.2.2 Hormone receptor agonists/antagonists Finerenone, a novel mineralocorticoid receptor antagonist, ameliorated defective mitophagy through the PI3K/Akt/eNOS signaling axis, thereby alleviating renal inflammation and fibrosis (Yao et al., 2023)

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