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Respir Med 100:846854 Hasnis E, Bar-Shai M, Burbea Z, Reznick AZ (2007) Mechanisms underlying cigarette smoke-induced NF-kappaB activation in human lymphocytes: the role of reactive nitrogen species

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This systematic review aimed to assess NRT's effectiveness on OST cessation and reduction rates, addressing gaps in prior studies by incorporating recent research across diverse populations, including developing and developed countries

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Ventilation (V) refers to the movement of air into and out of the alveoli, while perfusion (Q) relates to the blood flow to the alveolar capillaries (Hopkins 2020)