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Given their potential intermediate role in the causal chain between smoking/HIV and ageing parameters, a mediation analysis would have been of interest but was not performed due to the limited sample size of our study to test such more complex relationships

Below are the main Marlboro cigarette product lines, their nicotine content, and nicotine yield: Table 1: Marlboro Cigarettes Nicotine Content & Yield Nicotine content and yield vary significantly across different cigarette brands

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