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Future studies with better experimental designs are needed to confirm the observed findings, providing greater robustness to the evidence regarding the aspects analyzed in relation to EC use

Although schools were purposively stratified by gender composition to maximise diversity, selection relied on local gatekeepers, which may have introduced recruitment bias despite efforts to include staff and pupils of different ages, backgrounds, and smoking exposures

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Again, IQOS is considered a cigarette product, not an e-cigarette, which is why it needs to pass the regulatory hurdle before it can be sold here

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