Earlier observations of Pryor and his associates (8) suggested that the principal relatively stable radical in cigarette tar might be quinone/hydroquinone/semiquinone complex which was an active redox system and that this redox system was capable of reducing molecular oxygen to produce superoxide, leading to hydrogen peroxide and hydroxyl radicals, which may eventually lead to oxidative damage of biological macromolecules

Research from the British medical journal The Lancet in August called them more effective than nicotine patches in helping smokers quit.Early e-cigarette designs were drawn up in the US as early as the 1960s, but Hon is acknowledged among industry commentators as the first person to develop a viable commercial version.He came up with his design in 2003 while working as a medical researcher and trying to quit a pack-a-day habit developed in his teens."In the evenings I sometimes forgot to take off my nicotine patch, which gave me nightmares all night," he said.In one dream Hon said he found himself drowning in a sea that turned into a cloud of vapour, giving him inspiration for the product which he scribbled down on a bedside notepad.After a year spent perfecting the design, he said, sales took off and by 2006 Ruyan was "producing 24 hours a day with demand still exceeding supply".But that same year, media reports that described his products as addictive and causing heart attacks dented sales.China's tobacco sales administration accused the company of irresponsible advertising and recommended Beijing shops stop selling its products.Hon said China's state-run tobacco industry -- a powerful lobby that contributes as much as 10 percent to total government revenues, according to the US-based Brookings Institution -- was wary of the competition."All tobacco companies disliked our products, especially the large ones, and they have influence over governments," Hon said, accusing the industry of driving some of the negative coverage."It's like how the inventor of a perpetual motion machine would receive pressure from the energy industry."Meanwhile rival firms sprang up in China and abroad

To compensate for that, Google keywords and search traffic data were used to see what side effects were most searched for
E-Cigarettes dont work this way
The risk of developing esophageal cancer in light smokers compared to regular smokers is unclear
treatments only manage symptoms, making prevention the only effective protection