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Overall, out of the eight longitudinal and cross-sectional studies, only one found an increased cancer risk

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Research shows that most adult smokers (57%) began when they were minors

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[1] Carbon monoxide primarily causes adverse effects by combining with hemoglobin to form carboxyhemoglobin (symbol COHb or HbCO), which prevents the blood from carrying oxygen and expelling carbon dioxide as carbaminohemoglobin

Public Health Consequences of E-cigarettes