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Age and duration of smoking had very high VIFs (41.7 and 35.3, respectively), exceeding the conservative threshold of 5, and were excluded from multivariable analysis due to their non-significant bivariate associations ( p 0.25)

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Indeed, tumoral LKB1 expression was lower in smokers than in nonsmokers with NSCLC (Fig

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doi: 10.2165/11538190-000000000-00000