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117 FDA interprets these documents to include "cell-based, tissue-based, animal, or human studies, computational toxicology models, information on addiction, intentions to use, cognition, emotion, motivation, and other behavioral effects at both the population-level (epidemiology) as well as the individual level (such as abuse liability)." 118 FDA has the authority to require, by regulation, tobacco product manufacturers and importers to establish and maintain records to ensure that tobacco products are not adulterated or misbranded and to otherwise protect public health

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[107] Due to this design, some metals are potentially found in the e-cigarette vapor

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As of December 2009, 65 Bloom stores were in North Carolina, South Carolina, Maryland, and Virginia