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For neurological involvement, hydroxocobalamin 1mg should be given on alternate days until no further improvement, before moving to maintenance

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NAD+ is required for ATP production, and topping up a declining pool is the rationale [1]

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This hormonal preservation is especially relevant for individuals with existing endocrine considerations, those prone to stress-related eating, or anyone seeking to avoid the systemic hormonal disruptions that often accompany aggressive fat loss interventions