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The efficacy and safety of varenicline was evaluated in a randomized, double-blind, placebo-controlled study of 312 patients aged 12 to 19 years, who smoked an average of at least 5 cigarettes per day during the 30 days prior to recruitment, had a score of at least 4 on the Fagerstrom Test for Nicotine Dependence scale, and at least one previous failed quit attempt

We may if we wish think of them as metaphors- as shards of ancient sculpture, or architecture fragments, or the discarded costumes of kings and jugglers- but it is important that we remember also their inconsequence, for otherwise their new nobility and eloquence, their classical rectitude, would not so deeply touch our hearts.

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Set in the punk-rock scene of the early 2000s and vibrating with the intense ache of bad choices and deep longing, A Cigarette Lit Backwards is a needle-sharp portrait of a young woman and how far shell go to find acceptance