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Following the passage of Proposition 99, which imposed a 25-cent tax on every pack of cigarettes sold in the state of California in 1988, the county created the San Mateo County Tobacco Education Coalition (TEC)[2]This organization is particularly responsible for information and communication campaigns designed to prevent young people from becoming addicted to nicotine and to raise awareness of the many harmful effects of tobacco and nicotine products

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This is a limitation to keep in mind when working with immortalized cell lines