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These results suggest that nicotine may be the active compound in cigarette smoke responsible for carcinogenesis in the esophagus

Among patients who underwent open lobectomy surgery, those exposed to secondhand smoke had significantly lower postoperative arterial oxygen tension than nonsmoking controls, and required larger amounts of morphine consumption [46]

So, in most cases, airlines permit the use of nicotine pouches during flights because theres no combustion, vapour, or excessive odour

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Nicotine addiction was highlighted as a persistent issue, with e-cigarettes perpetuating dependence rather than serving as a smoking cessation tool