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So, that's a different nature of exposure, and we can capture the effects of that difference, said Niyati Jain, co-first author and a PhD student in the Committee on Genetics, Genomics, and Systems Biology

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Think of it like drinking coffee on an empty stomach: the stimulant effects hit harder and faster, often in a not-so-pleasant way

OR [99% CI] 1.32 [1.111.58])

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The risk factors with the strongest empirical support, presented based on the number of studies and the quality of the evidence according to GRADE 46 , are: 1) greater acceptance and use of ECs in their social circles (family or friends), reported in 13 studies, of which only one is of high quality 59