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Epithelium was stripped and incubated in 0.25% Trypsin-EDTA for 30 min, shaking at 37 C to generate a single cell suspension

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Unlike regular gum, which is chewed until the flavour fades, nicotine gum must be chewed using a specific technique for it to work effectively

While smoking offers intuitive control, edibles demand meticulous planning to avoid overconsumption

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