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Nicotine acts as a stimulant that creates a pleasant feeling due to the nicotine binding with nicotinic cholinergic receptors in the brain

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This matters because contact time with the filter affects how much can be trapped

[2] Prud'homme M, Cata R, Jutras-Aswad D

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The patient immediately received intravenous infusion of 10% potassium chloride solution and oral administration of 20 mL of 10% potassium chloride solution