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Project III: Models of Human Smoking related Diseases: What is the Best Mimic of Human Disease? Center for Tobacco Regulatory Science and Lung Health (TCORS) Epithelial changes in COPD. Cigarette smoke, reactive oxygen species, Download Scientific Diagram Nicotine causes damage to epithelial cells. In various systems, Download Scientific Diagram E cigarettes disrupt lung function and raise risk of infection Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium Nature Communications Figure 10.4, Overview of immune defects caused by smoking in the lungs The Health Consequences of Smoking50 Years of Progress NCBI Bookshelf

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