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However, pathological and high-resolution imaging evidence has changed this understanding: progressive destruction and loss of terminal bronchioles can precede alveolar parenchymal destruction or a significant decline in overall lung function, suggesting that SAD may be the initial step in the disease cascade ( This paradigm shift also explains why patients with similar traditional lung function measures exhibit significant differences in the burden of airway structural damage and clinical outcomes

When comparing LC characteristics with FC characteristics, an independent two-sample t-test was used to evaluate statistical significance

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A homemade citrus spray offers a simple, natural method to rid your hair of lingering bonfire odors

Front Immunol (2022) 13:975914