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Two approaches were used: the TWIST methylome panel ( ~ 4 million CpG sites) and ONT sequencing ( ~ 21 million CpG sites)

Of these websites, over 90% implicitly or explicitly claimed that e-cigarettes have a health benefit, 76% claimed the product does not produce secondhand smoke, and 64% advertised that e-cigarettes can help users quit smoking

Namely, these aforementioned studies have been able to detect risk factors that may help to identify a population of never smokers who are contenders for screening and to propose biomarkers that can aid in evaluating risk of LCNS at an individual level

These factors collectively pose risks to profit margins, even as companies attempt to offset pressures through pricing actions and efficiency initiatives

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