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In 2011, the IOM issued a further report (Institute of Medicine2011) on the science needed to assess such products, which it identified as "modified-risk tobacco products" or MRTPs

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Antisocial behavior that can, if it goes unabated, lead eventually to more serious problems as adolescents mature into adulthood. Romer said the study was prompted in part by previous research showing a connection between conduct problems and marijuana use

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