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Anti-malarial medication is usually started a few days before travel (so that the drug has time to reach sufficient levels in your blood), is taken at regular intervals (usually daily or weekly) for the duration of the trip and is then continued for as long as four weeks after leaving the affected region, since parasites can still emerge from the liver during this period

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Henri Hallopeau described it as a variant of lichen planus in 1889 and, while it is a distinct condition in its classic form, there are sometimes overlap features between the two disorders

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