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They used a first-generation (V2 standard Cig with cartomizer) and a new-generation device (EVIC set at 9 watts with EVOD atomizer) on two separate days in a randomized cross-over design

The acute effects of nicotine on the heart are: Increase in systolic blood pressure, heart rate, cardiac output Vasoconstriction Carbon monoxide reduces the availability of oxygen to the heart

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At the end of the day, the best quitting method is the one that actually works for the individual and helps them stay off cigarettes long-term.

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