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Varenicline The efficacy and safety of varenicline in helping hospitalized patients stop smoking, even in those with acute coronary syndrome, has been clearly demonstrated in 3 out of 4 clinical trials.1315,22 Varenicline should be used at the standard dose for a period of 12 weeks.12,33,34 In patients with a high degree of dependence or chronic respiratory diseases, it is highly advisable to use it at the dose and for the duration indicated by scientific societies such as the Spanish Society of Pulmonology and Thoracic Surgery and the European Respiratory Society.33,34 The major drawback for the use of varenicline in hospitalized patients is the need to administer it for 1 week before it becomes fully effective

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