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The variability in the primary outcome number of cigarettes smoked per day was higher than expected based on our earlier pilot study, leading to a large sample size re-estimation in the interim analysis

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"Therefore, pulling cigarettes makes sense." Whether CVS competitors will also pull cigarettes depends on their margins and on how important tobacco is to their bottom lines, he said

Its more of a hypothetical argument thats often made when talking about e-cigarette use in young people, but no data supports the theory, and it defies biological plausibility, he says