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Warning labels on cigarette packages could soon be more graphic, warning that Smoking reduces blood flow to the limbs, which can require amputation, and Smoking causes bladder cancer, which can lead to bloody urine. The US Food and Drug Administration on Thursday issued a proposed rule that requires tobacco companies to place new graphic health warnings on cigarette packages and in advertisements

Although e-cigarettes were first proposed in 1927 by Joseph Robinson 1 , it was only in the early 2000s that the 1st generation of e-cigarettes or cig-a-likes became commercially available 2,3,4

The advocates also say countries should be free to decide how best to protect public health, without being second-guessed by unelected trade panels

Trials of smoking-reduction interventions have also found that these can lead to increased quitting when combined with nicotine replacement therapy