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TLR9, expressed in endosomes, was reported to recognize cell-free DNA released from degenerated cells in macrophages, which promotes vascular inflammation and atherosclerosis in apolipoprotein E knockout mice [14]

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The headline finding is that people who switched from cigarettes to heated tobacco had lower levels of exposure to harmful chemicals than those who kept smoking, but higher levels of these toxins than those who stopped using tobacco altogether

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